As chronic wounds, diabetic ulcers, surgical incisions, and other wound types become increasingly complex, traditional dressings gradually reveal limitations in moisture retention, antibacterial properties, breathability, and bioactivity. To meet the modern demands for efficient, safe, and smart wound care solutions, functional hydrogel materials have emerged. PAM/CS hydrogel (composed of polyacrylamide and chitosan) demonstrates remarkable advantages in wound healing due to its excellent gel-forming ability, biocompatibility, and tunable properties.
Litchlab possesses mature PAM/CS hydrogel preparation technology and customization capabilities, providing clients with multi-specification, multi-performance hydrogel products to meet different stages of pharmaceutical R&D needs.
Product Name: PAM/CS Composite Hydrogel Dressing
Product Overview:
This product is a soft, transparent, three-dimensional hydrogel network that can be directly applied to the wound surface. It offers excellent fluid absorption, film-forming ability, and bioactivity to accelerate wound repair. It is suitable for a variety of wound care applications.
Technical Parameters:
Gel water content: >90%
pH adaptability: 4.5–8.0
Biodegradability: High
Antibacterial efficacy (inhibition rate): >95% (against E. coli and S. aureus)
Material Composition:
Polyacrylamide (PAM)
Chitosan (CS)
Deionized water
Crosslinking agents (optional, natural/biodegradable)
Physical Properties:
Excellent softness and adhesion to wound surfaces without displacement
Microporous structure supporting gas exchange and exudate absorption
Non-adhesive to wounds, reducing pain during dressing changes
For drug-loading applications, the hydrogel surface or structure can be functionally modified, enabling precise design of drug release profiles.
Performance Advantages:
Combines PAM’s strong gelation with CS’s natural antibacterial properties
Good mechanical strength and bioactivity
Maintains a moist wound environment while preventing infection
Core Functions:
Prolonged hydration, promoting granulation tissue growth
Antibacterial and anti-inflammatory effects to reduce infection risk
Adjustable drug delivery system for controlled release
Facilitates epithelial cell migration, accelerating wound closure
For drug encapsulation, Litchlab offers precise custom hydrogel services, extending drug efficacy and enhancing stability across various drug types.
Comparison with Competing Products:
Superior bioactivity and comfort compared with traditional nonwoven fabrics, foam dressings, and silver-ion dressings
Composite PAM/CS hydrogel shows synergistic properties compared with single-component PAM or CS hydrogels
Economic Advantages:
Mature synthesis process with controllable costs
Supports large-scale and customized production
Longer usage cycles reduce replacement frequency and overall care costs
Cost-effectiveness:
Stable raw material sources
Supports single-use and multiple-use formats
Economically friendly for both medical institutions and patients
Surgical incision dressings
Diabetic foot ulcer care
Venous ulcer care
Pressure ulcers and trauma care
Post-medical-aesthetic treatment dressing
Litchlab ’s robust pilot-scale platform allows lab-formulated hydrogels to be scaled up rapidly to industrial levels, ensuring smooth transition to clinical and commercial stages.
Design Stage:
Determine drug loading, gel strength, and thickness according to customer requirements
Provide multiple formats (patch, injectable, pre-formed dressing)
Manufacturing:
Controlled temperature and vacuum stirring synthesis
Key production steps compatible with GMP standards for medical-grade output
Large-scale production capacity ensures continuous supply
Installation and Use:
Sterile packaging for direct use in hospitals or at home
User manuals and instructions reduce operational complexity
Maintenance and Storage:
Stable for over 6 months under low-temperature conditions
Easy disposal after use without special treatment
PAM/CS hydrogel represents a new generation of medical dressings, excelling in moisture therapy, antibacterial control, controlled drug release, and biocompatibility. It is a highly promising solution for wound repair in pharmaceutical R&D.
Litchlab looks forward to collaborating with R&D institutions and pharmaceutical companies to advance hydrogel technology applications and meet diverse medical research needs, maximizing industrial value.
In the future, this material may further integrate smart responsive mechanisms (e.g., temperature-sensitive, pH-responsive) and expand into wearable medical dressings and self-healing wound repair systems, supporting precision therapy and personalized care development.
